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Our lab works at the interface between physics, nanotechnology, and biology. We combine quantitative super-resolved fluorescence microscopy, single-particle tracking, single-molecule fluorescence techniques and statistical physics/modelling to study biological systems at various scales, ranging from individual biological macromolecules (proteins, DNA, RNA) to individual cells/bacteria. We aim to understand quantitatively the fundamental physics that controls the central processes that remain unknown/unclear. (read more about the Science in our lab)

 

News

  • 06/2018: Together with Dr. Egan, we got the Chancellor’s Discovery, Creativity, Innovation, and Collaboration grant.
  • 05/2018: A USDA proposal that we are involved was funded.
  • 05/2018: Congratulations to Austin Brown and Tiffany Marcelle for graduation!
  • 02/2018: Congratulations to Austin Brown for being accepted to Medical School!
  • 01/2018: Congratulations to Jack Freeland for being awarded an Honors College Research Grant!
  • 12/2017: Mohammad’s paper (“An Experiment-Based Model Quantifying Antimicrobial Activity of Silver Nanoparticles on Escherichia coli”, a collaboration with Dr. Chen’s group at University of Arkansas) is formally accepted and published by RSC Advances (see Publication).
  • 10/2017: We receive a grant from the Honors College, which will help us to build the second super-resolution fluorescence microscope in our lab.
  • 09/2017: Congratulations to Sai Divya Challapalli on passing her final defense for her M.S. degree!
  • 09/2017: Jack Jiang’s work is reported by UARK Newswire (link)
  • 07/2017: Congratulations to Mohammad Haque on passing his final defense for his M.S. degree!
  • 06/2017: Our proposal on Ag+ gets funded by Arkansas Biosciences Institute.
  • 06/2017: Jack Jiang’s paper (“Robust nonparametric quantification of clustering density of molecules in single-molecule localization microscopy”, co-authored by Sai Divya and our collaborators) is formally accepted by PLOS ONE.
  • 04/2017: Congratulations to Austin Brown, Collin Brown and Tiffany Marcelle in our lab for winning several physics scholarships.
  • 03/2017: Our paper “Spatial distribution of high copy number plasmids in bacteria” is now published in Plasmids.
  • 06/2016: Our paper “Quantitative localization microscopy in combination with DNA smFISH reveals new features of the organization of high-copy number plasmids in bacteria” is formally accepted by Biophysical Journal.
  • 06/2016: Our proposal on plasmids gets funded by Arkansas Biosciences Institute.
  • 04/2016: Sai Divya Challapalli gave a poster presentation at the 100th Arkansas Academy of Science Meeting.

 

Funding

The research in our lab has been supported by the following funding agencies.

University of Arkansas    HFSP    ABI    University of Arkansas Honors College